Introduction.Microleakage is defined as the clinically undetectable seepage of oral fluids containing bacteria and debris between cement layer and tooth restoration.Objective.This in vitro study investigated the effect of different dental cements (zinc-phosphate, polycarboxylate, glass-ionomer and resin cement) on microleakage in different ceramic
Dynamics of HIV-containing compartments in macrophages reveal sequestration of virions and transient surface connections.
During HIV pathogenesis, infected macrophages behave as lochby venture pouch "viral reservoirs" that accumulate and retain virions within dedicated internal Virus-Containing Compartments (VCCs).The nature of VCCs remains ill characterized and controversial.Using wild-type HIV-1 and a replication-competent HIV-1 carrying GFP internal to the Gag prec
Tumor xenograft modeling identifies an association between TCF4 loss and breast cancer chemoresistance
Understanding the mechanisms of cancer therapeutic click here resistance is fundamental to improving cancer care.There is clear benefit from chemotherapy in different breast cancer settings; however, knowledge of the mutations and genes that mediate resistance is incomplete.In this study, by modeling chemoresistance in patient-derived xenografts (P
Precision worm control in grazing lambs by targeting group treatment based on performance of sentinels
Given the economic impact of gastrointestinal nematode infection on livestock farming worldwide, and increasing anthelmintic resistance, it is imperative to develop practical, efficient and sustainable control strategies.Targeted selective treatment (TST), whereby anthelmintic treatments are administered to animals individually, based on selection